68Ga-DOTANOC PET/CT in Adrenal Schwannoma

Clin Nucl Med. 2023 Jan 1;48(1):e22-e23. doi: 10.1097/RLU.0000000000004444.

Abstract

Adrenal schwannoma is a rare adrenal incidentaloma. It is a benign tumor arising from the Schwann cells. Differentiating benign from malignant adrenal lesions requires a combination of clinical, biochemical, imaging, and histopathological findings. 68Ga-DOTANOC PET/CT is one of the sensitive imaging modalities to detect adrenal lesions such as pheochromocytoma. Multiple benign and malignant lesions show somatostatin receptor expression causing a high probability of false-positive findings on somatostatin receptor imaging. We present a case of adrenal incidentaloma positive on 68Ga-DOTANOC PET, which revealed a benign adrenal spindle cell tumor on histopathology.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Neoplasms* / diagnostic imaging
  • Humans
  • Multimodal Imaging
  • Neurilemmoma* / diagnostic imaging
  • Organometallic Compounds*
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography / methods
  • Receptors, Somatostatin / metabolism
  • Tomography, X-Ray Computed / methods

Substances

  • 68Ga-DOTANOC
  • Receptors, Somatostatin
  • Organometallic Compounds

Supplementary concepts

  • Adrenal incidentaloma