Alveolar soft part sarcoma in childhood and adolescence: Report of three cases and review of literature

Yudi Zhang; Ying Wang; Hao Wang; Chuan Wen; Xiaochuan Wu

doi:10.3389/fped.2022.937112

Alveolar soft part sarcoma in childhood and adolescence: Report of three cases and review of literature

Front Pediatr. 2022 Nov 18:10:937112. doi: 10.3389/fped.2022.937112. eCollection 2022.

Authors

Yudi Zhang¹, Ying Wang¹, Hao Wang², Chuan Wen¹, Xiaochuan Wu¹

Affiliations

¹ Department of Pediatrics, Second Xiangya Hospital, Central South University, Changsha, China.
² School of Instrument and Electronics, North University of China, Taiyuan, China.

Abstract

Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma with unique tumor characteristics, which is rare in children. Herein, we present the immunophenotype, treatment, and prognosis of three children with ASPS from The Second Xiangya Hospital of Central South University, and 51 children with ASPS have been reported in the previous literature, along with a focused review of the clinical features, pathological features, differential diagnosis, treatment, and prognosis of ASPS in pediatric patients.

Keywords: TFE3; alveolar soft part sarcoma; children; pathology; treatment.

Publication types

Review