Nanoformulation-based Drug Delivery System for Viral Diseases

Pharm Nanotechnol. 2023;11(2):105-126. doi: 10.2174/2211738511666221201154154.

Abstract

Viral diseases are one of the major causes of mortality worldwide. The emergence of pandemics because of the COVID virus creates a dire need for an efficient mechanism to combat the disease. Viruses differ from other pathogenic infections; they render the host immune system vulnerable. One of the major challenges for developing antivirals is the resistance developed by the overuse of drugs, which is inevitable as most viral diseases require a large number of doses. Viral infection detection, prevention, and treatment have significantly benefitted from developing several innovative technologies in recent years. Nanotechnology has emerged as one of the most promising technologies because of its capacity to deal with viral infections efficiently and eradicate the lagging of conventional antiviral drugs. This review briefly presents an overview of the application of nanotechnology for viral therapy.

Keywords: Nanotechnology; lipid-based nanoformulation; liposome; polymer-based nanoformulation; viral diseases; viral therapy.

Publication types

  • Review

MeSH terms

  • Antiviral Agents
  • COVID-19*
  • Drug Delivery Systems
  • Humans
  • SARS-CoV-2
  • Virus Diseases* / drug therapy

Substances

  • Antiviral Agents