Performance evaluation of buildup bolus during external radiotherapy of mastectomy patients: treatment planning and film dosimetry

Med Biol Eng Comput. 2023 Feb;61(2):435-444. doi: 10.1007/s11517-022-02721-x. Epub 2022 Dec 3.

Abstract

A buildup bolus is used during the post-mastectomy radiotherapy (PMRT) to overcome under-dosage issues in the chest wall. The current study is aimed at evaluating the performance of a bolus in dose enhancement through both film dosimetry and treatment planning approaches. Twenty patients were enrolled in current research. The received dose by the skin at the lateral and medial regions of the chest wall in the presence and absence bolus was evaluated. Film dosimetry results showed that the presence of the bolus can averagely increase the skin dose by about 80% (P value < 0.001) and 92% (P value < 0.001) in lateral and medial regions, respectively. No significant difference was observed between the measured and treatment planning system (TPS)-calculated dose values in the presence of bolus. The presence of the bolus can considerably increase the absorbed dose by superficial chest wall regions. The TPS shows a favorable performance in superficial dose calculations in the presence of the buildup bolus. Hosseini et al.: demonstration of implemented research in the current study.

Keywords: Breast cancer; Buildup bolus; Film dosimetry; ISOgray TPS; PMRT; Treatment planning.

MeSH terms

  • Breast Neoplasms* / radiotherapy
  • Breast Neoplasms* / surgery
  • Female
  • Film Dosimetry*
  • Humans
  • Mastectomy
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted
  • Skin