There is a Good Consistency Between Reflux Symptom Score-12 and Reflux Symptom Index in Chinese Population

Ruimin Yang; Fangfang Liang; Ru Tian; Yang Yao; Ming Zhang; Xiaowen Li

doi:10.1016/j.jvoice.2022.11.021

There is a Good Consistency Between Reflux Symptom Score-12 and Reflux Symptom Index in Chinese Population

J Voice. 2022 Nov 29:S0892-1997(22)00373-3. doi: 10.1016/j.jvoice.2022.11.021. Online ahead of print.

Authors

Ruimin Yang¹, Fangfang Liang², Ru Tian³, Yang Yao², Ming Zhang², Xiaowen Li²

Affiliations

¹ Department of Otolaryngology, Hebei Langfang people's Hospital, Hebei, China. Electronic address: yangruimin_nepal@163.com.
² Department of Otolaryngology, Hebei Langfang people's Hospital, Hebei, China.
³ Department of Otolaryngology, Langfang Hospital of traditional Chinese medicine, Hebei, China.

PMID: 36460539
DOI: 10.1016/j.jvoice.2022.11.021

Abstract

Objective: To investigate the consistency between the Reflux Symptom Score-12 (RSS-12) and Reflux Symptom Index (RSI) in Chinese people.

Methods: Patients with symptoms of LPR from the outpatient otorhinolaryngology-head and neck surgery clinic were included. All included patients completed the RSS-12 and RSI. The patient with RSS-12>11 or RSI>13 suggested possible LPR. For the patients with RSI >13 or RSS-12>11, they were treated using diet recommendations and were prescribed a twice-daily pantoprazole for 12 weeks. The consistency between the RSS-12 and RSI was compared with the weighted Cohen's kappa statistic.

Results: A total of 258 patients were included. The mean scores for RSS-12 and RSI were 13.21±17.31 and 12.86±6.15, respectively. The positive rate of LPR was 17.44% based on the RSI, and 24.42% based on the RSS-12. The kappa value between the RSS-12 and RSI was 0.736 (P < 0.001). Following 12 weeks of treatment, there was a significant reduction in both RSI and RSS-12. Based on the RSI, 73% of patients had a good treatment response, whereas according to the RSS-12, 85% of patients had a good treatment response.

Conclusion: There is a good consistency between RSS-12 and RSI, meaning that the RSS-12 is a feasible LPR initial screening tool. The RSS-12 provides a more comprehensive evaluation of reflux symptoms and treatment effect than RSI in patients with LPR.

Keywords: Consistency; LPR; RSI; RSS-12.