Evaluation of the predictive factors of the short-term effects of a multidisciplinary rehabilitation in COVID-19 survivors

J Int Med Res. 2022 Nov;50(11):3000605221138843. doi: 10.1177/03000605221138843.

Abstract

Objective: Functional impairments after coronavirus disease 2019 (COVID-19) constitute a major concern in rehabilitative settings; however, evidence assessing the efficacy of rehabilitation programs is lacking. The aim of this study was to verify the clinical characteristics that may represent useful predictors of the short-term effectiveness of multidisciplinary rehabilitation.

Methods: In this real-practice retrospective pre-post intervention cohort study, the short-term effectiveness of a multidisciplinary patient-tailored rehabilitation program was assessed through normalized variations in the Functional Independence Measure in post-acute care patients who had overcome severe COVID-19. Biochemical markers, motor and nutritional characteristics, and the level of comorbidity were evaluated as predictors of functional outcome. Length of stay in the rehabilitation ward was also considered.

Results: Following rehabilitation, all participants (n = 53) reported a significant decrease in the level of disability in both motor and cognitive functioning. However, neither motor and nutritional characteristics nor comorbidities played a significant role in predicting the overall positive change registered after rehabilitation.

Conclusions: The results support the existing sparse evidence addressing the importance of an early rehabilitation program for patients who received intensive care and post-acute care due to severe COVID-19.

Keywords: COVID-19; Functional Independence Measure; functional impairment; multidisciplinary rehabilitation; post-acute care; rehabilitation effectiveness..

MeSH terms

  • COVID-19*
  • Cohort Studies
  • Critical Care
  • Humans
  • Retrospective Studies
  • Survivors