Anisometropic amblyopia: A review of functional and structural changes and treatment

Eur J Ophthalmol. 2023 Jul;33(4):1529-1535. doi: 10.1177/11206721221143164. Epub 2022 Nov 29.

Abstract

Amblyopia is the decreased best-corrected visual acuity (BCVA) in one or both eyes caused by the abnormal processing of visual input during development. One common cause of amblyopia is anisometropia, which has attracted widespread attention. Many structural changes occur in the primary and extrastriate visual areas of the cerebral cortex, as well as in the eyes, in patients with anisometropic amblyopia. Understanding these mechanisms has provided a favorable theoretical basis for treating anisometropic amblyopia. This article reviews the functional and anatomical changes and progress toward the treatment of anisometropic amblyopia.

Keywords: Anisometropic amblyopia; functional changes; lazy eye; structural changes; treatments.

Publication types

  • Review

MeSH terms

  • Amblyopia* / therapy
  • Anisometropia* / complications
  • Anisometropia* / therapy
  • Eye
  • Humans
  • Visual Acuity