A nodule peptide confiscates haem to promote iron uptake in rhizobia

Jawahar Singh; Oswaldo Valdés-López

doi:10.1016/j.tplants.2022.11.005

A nodule peptide confiscates haem to promote iron uptake in rhizobia

Trends Plant Sci. 2023 Feb;28(2):125-127. doi: 10.1016/j.tplants.2022.11.005. Epub 2022 Nov 26.

Authors

Jawahar Singh¹, Oswaldo Valdés-López²

Affiliations

¹ Laboratorio de Genómica Funcional de Leguminosas, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, México.
² Laboratorio de Genómica Funcional de Leguminosas, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, México. Electronic address: oswaldovaldesl@unam.mx.

PMID: 36443185
DOI: 10.1016/j.tplants.2022.11.005

Abstract

Nodule cysteine-rich (NCR) peptides have a major role in the differentiation of endocytosed bacteria into nitrogen-fixing bacteroids. A recent paper by Sankari et al. indicates that NCR247 is essential for the uptake of iron, a mineral nutrient required for nitrogenase activity. Furthermore, the special ability of NCR247 to sequester haem suggests potential applications for human health.

Keywords: human health; inverted repeat-lacking clade (IRLC); legumes; nitrogenase; nodule cysteine-rich (NCR) peptides; symbiotic nitrogen fixation.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Bacteria / metabolism
Humans
Iron
Nitrogen Fixation
Peptides / metabolism
Rhizobium*
Symbiosis

Substances

Iron
Peptides