Risk factors and survival in patients with COVID-19 in northeastern Brazil

Ana Tereza Fernandes; Eujessika K Rodrigues; Eder R Araújo; Magno F Formiga; Priscilla K Sá Horan; Ana Beatriz Nunes de Sousa Ferreira; Humberto A Barbosa; Paulo S Barbosa

doi:10.1371/journal.pone.0278213

Risk factors and survival in patients with COVID-19 in northeastern Brazil

PLoS One. 2022 Nov 28;17(11):e0278213. doi: 10.1371/journal.pone.0278213. eCollection 2022.

Authors

Ana Tereza Fernandes¹, Eujessika K Rodrigues², Eder R Araújo¹, Magno F Formiga³, Priscilla K Sá Horan⁴, Ana Beatriz Nunes de Sousa Ferreira¹, Humberto A Barbosa⁵, Paulo S Barbosa²

Affiliations

¹ Department of Physical Therapy, State University of Paraiba, Campina Grande, Brazil.
² Center of Technology Strategies in Health, State University of Paraiba, Campina Grande, Brazil.
³ Department of Physical Therapy, Federal University of Ceara, Fortaleza, Brazil.
⁴ Don Luiz Gonzaga Fernandes Trauma and Emergency Hospital, Campina Grande, Brazil.
⁵ Federal University of Alagoas, Maceio, Brazil.

Abstract

Background: Knowledge about the epidemiology and risk factors surrounding COVID-19 contributes to developing better health strategies to combat the disease.

Objective: This study aimed to establish a survival analysis and identify the risk factors for patients with COVID-19 in an upper middle-income city in Brazil.

Methods: A retrospective cohort study was conducted with 280 hospitalized patients with COVID-19. The eCOVID platform provided data to monitor COVID-19 cases and help the communication between professionals.

Results: Age ≥ 65 years was associated with decreased survival (54.8%), and females had a lower survival rate than males (p = 0.01). Regarding risk factors, urea concentration (p<0.001), hospital length of stay (p = 0.002), oxygen concentration (p = 0.005), and age (p = 0.02) were associated with death.

Conclusion: Age, hospital length of stay, high blood urea concentration, and low oxygen concentration were associated with death by COVID-19 in the studied population. These findings corroborate with studies conducted in research centers worldwide.

Copyright: © 2022 Fernandes et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Brazil / epidemiology
COVID-19* / epidemiology
Female
Humans
Male
Oxygen
Retrospective Studies
Risk Factors

Substances

Oxygen

Grants and funding

Yes.This study was financed by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) (Finance Code CAPES EPIDEMIAS 09/2020-grand/award number:23038.013745/2020-69 to H.A.B) and Fundação de Apoio à Pesquisa do Estado da Paraíba – Brasil (FAPESQ) (Finance Code COVID-19 003/2020). The funders The funders had role in study design, decision to publish and preparation of the manuscript.