Successful surgical treatment of epithelioid hemangioendothelioma involving multiple liver lesions and bilateral lung nodules

Takatora Akizawa; Tomotaka Nishizawa; Sho Yamada; Hiroki Ota; Gen Kida; Yuta Tsukahara; Tomohiko Nakamura; Tomohiro Oba; Hideaki Yamakawa; Rie Kawabe; Shintaro Sato; Keiichi Akasaka; Masako Amano; Mitsuru Maki; Akiko Adachi; Haruyuki Ishii; Hidekazu Matsushima

doi:10.1016/j.rmcr.2022.101769

Successful surgical treatment of epithelioid hemangioendothelioma involving multiple liver lesions and bilateral lung nodules

Respir Med Case Rep. 2022 Nov 17:40:101769. doi: 10.1016/j.rmcr.2022.101769. eCollection 2022.

Authors

Takatora Akizawa^{1

2}, Tomotaka Nishizawa^{1

2}, Sho Yamada^{1

2}, Hiroki Ota¹, Gen Kida¹, Yuta Tsukahara¹, Tomohiko Nakamura¹, Tomohiro Oba¹, Hideaki Yamakawa¹, Rie Kawabe¹, Shintaro Sato¹, Keiichi Akasaka¹, Masako Amano¹, Mitsuru Maki³, Akiko Adachi⁴, Haruyuki Ishii², Hidekazu Matsushima¹

Affiliations

¹ Department of Respiratory Medicine, Japanese Red Cross Society Saitama Hospital, Saitama, Japan.
² Department of Respiratory Medicine, Graduate School of Medicine, Kyorin University, Tokyo, Japan.
³ Department of Thoracic Surgery, Japanese Red Cross Society Saitama Hospital, Saitama, Japan.
⁴ Department of Pathology, Japanese Red Cross Society Saitama Hospital, Saitama, Japan.

Abstract

Epithelioid hemangioendothelioma (EHE) affects many organs, particularly lung and liver, and typically presents as multiple lesions. Treatment for EHE is not yet standardized, but surgery is appropriate when lesions are resectable. In our patient, radiography revealed multiple bilateral pulmonary nodules, and CT showed several liver tumors. The liver masses and those in the right lung were removed during the initial surgery; pathology of hepatic specimens confirmed the diagnosis of EHE. During the second operation, the left lung nodules were excised, and all were EHEs. Surgical removal of multiorgan multinodular EHE is a viable treatment option, especially for young patients.

Keywords: Epithelioid hemangioendothelioma (EHE); Liver; Lung; Surgical treatment.

Publication types

Case Reports