Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics

Lucas J Osborn; Diana Villarreal; Noah Wald-Dickler; Jennifer Dien Bard

doi:10.1016/j.clinmicnews.2022.11.003

Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics

Clin Microbiol Newsl. 2022 Nov 15;44(22):199-208. doi: 10.1016/j.clinmicnews.2022.11.003. Epub 2022 Nov 18.

Authors

Lucas J Osborn¹, Diana Villarreal^{2

3}, Noah Wald-Dickler^{4

3}, Jennifer Dien Bard^{1

5}

Affiliations

¹ Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California.
² Department of Pediatrics, Maternal Child and Adolescent/Adult Center for Infectious Diseases and Virology, University of Southern California, Los Angeles, California.
³ Department of Medicine and Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California.
⁴ Department of Internal Medicine, Division of Infectious Diseases, University of Southern California, Los Angeles, California.
⁵ Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California.

Abstract

Monkeypox virus (MPXV) has garnered recent attention as outbreaks are continually reported outside historic regions of endemicity in Africa. Consequently, MPXV is becoming routinely included in the differential diagnosis of rash illnesses, requiring clinicians and laboratorians alike to quickly adapt to a new public health emergency. This review discusses the epidemiology, clinical presentation, and laboratory testing of MPXV in the context of recent outbreaks.

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