Cancer Cell Models for the Development of Anti-Cancer Drugs

Int J Mol Sci. 2022 Nov 21;23(22):14457. doi: 10.3390/ijms232214457.

Abstract

In the multi-factorial etiology of organ-site cancers by suspect human chemical carcinogens, oncogenic virus, activation of RAS, Myc and HER-2 oncogenes, inactivation of TP53, RB and APC tumor suppressor genes represent early-occurring genetic events [...].

Publication types

  • Editorial

MeSH terms

  • Antineoplastic Agents* / pharmacology
  • Antineoplastic Agents* / therapeutic use
  • Carcinogens
  • Humans
  • Neoplasms* / drug therapy
  • Oncogenes
  • Oncogenic Viruses

Substances

  • Antineoplastic Agents
  • Carcinogens

Grants and funding

This research received no external funding.