Mast Cells and Interleukins

Int J Mol Sci. 2022 Nov 13;23(22):14004. doi: 10.3390/ijms232214004.

Abstract

Mast cells play a critical role in inflammatory diseases and tumor growth. The versatility of mast cells is reflected in their ability to secrete a wide range of biologically active cytokines, including interleukins, chemokines, lipid mediators, proteases, and biogenic amines. The aim of this review article is to analyze the complex involvement of mast cells in the secretion of interleukins and the role of interleukins in the regulation of biological activities of mast cells.

Keywords: inflammatory cells; interleukins; mast cells; tumors.

Publication types

  • Review

MeSH terms

  • Biological Transport
  • Cell Count
  • Cytokines
  • Interleukins*
  • Mast Cells*

Substances

  • Interleukins
  • Cytokines

Grants and funding

This research received no external funding.