Post-COVID-19 Syndrome in Outpatients and Its Association with Viral Load

Int J Environ Res Public Health. 2022 Nov 17;19(22):15145. doi: 10.3390/ijerph192215145.

Abstract

Introduction: The COVID-19 pandemic is the result of the SARS-CoV-2 virus, which has caused more than 100 million infections and more than 2.5 million deaths worldwide, representing a serious public health problem. The gold method for detecting this virus is qRT-PCR, which is a semiquantitative technique where the viral load can be established through its cycle threshold (Ct). It has also been reported that COVID-19 generates long-term symptoms (post-COVID-19).

Methods: After three months, a survey was performed on 70 COVID-19 confirmed patients; subsequently, we divided them into four groups (persistent symptoms, chemo-sensitive, cognitive issues, and changes in habit) in order to determine the correlation between viral load and post-COVID-19 symptoms.

Results: Data show that fatigue, nervousness, anosmia, and diet changes are common long-term symptoms; in addition, a negative correlation was found between viral load and the number of post-COVID-19 symptoms.

Conclusion: COVID-19 generates long-term symptoms which can cause problems with psychological and social repercussions.

Keywords: SARS-CoV-2; mental health; perception; post-COVID-19 syndrome; viral load.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19*
  • Humans
  • Outpatients
  • Pandemics
  • Post-Acute COVID-19 Syndrome
  • SARS-CoV-2
  • Syndrome
  • Viral Load

Grants and funding

This research was funded by Consejo Nacional de Ciencia y Tecnología (CONACYT) grant number 314327 “Filtro basado en la detección molecular del virus SARS-CoV-2 para la población de Nayarit, México”.