The use of sedation to examine children is common in hospitals. MRI examinations require sedation when applied to pediatric patients, because of the high magnetic field and noisy environment, but complications such as respiratory failure and cardiac arrest have occurred in Japan. Unfortunately, there is no risk-free sedation. In order to perform sedation safely, it is necessary to understand the Recommendation on pediatric sedation for MRI examinations, which was published in 2020. Restrictions on oral intake prior to the exam and the 2-4-6 rules must be adhered to in order to avoid vomiting, and patients must be monitored every 5 minutes during the exam. In addition, non-sedative MRI with the use of videos and preparation tools should be performed more often.