Recommendations for the diagnosis and treatment of hypoglycaemia after bariatric surgery

Endocrinol Diabetes Nutr (Engl Ed). 2022 Nov;69(9):723-731. doi: 10.1016/j.endien.2021.09.005. Epub 2022 Nov 21.

Abstract

Postprandial hyperinsulinaemic hypoglycaemia is a common complication of bariatric surgery. Although in general its evolution is mild and self-limited, it can lead to neuroglycopaenia and compromise the patient's safety and quality of life. The aim of this document is to offer some recommendations to facilitate the clinical care of these complex patients, reviewing the aetiopathogenesis, its diagnosis and treatment that, sequentially, will include dietary and pharmacological measures and surgery in refractory cases. In the absence of high-quality studies, the diagnostic and therapeutic approach proposed is based on the consensus of experts of the Grupo de Obesidad de la Sociedad Española de Endocrinología y Nutrición [Obesity Group of the Spanish Society of Endocrinology and Nutrition], GOSEEN. Those undergoing bariatric surgery should be informed of the possibility of developing this complication.

Keywords: Bariatric surgery; Cirugía bariátrica; Hiperinsulinismo; Hipoglucemias; Hyperinsulinism; Hypoglycaemia; Morbid obesity; Neuroglucopenia; Neuroglycopaenia; Obesidad mórbida.

Publication types

  • Review

MeSH terms

  • Bariatric Surgery* / adverse effects
  • Endocrinology*
  • Humans
  • Hypoglycemia* / diagnosis
  • Hypoglycemia* / etiology
  • Hypoglycemia* / therapy
  • Obesity / diagnosis
  • Obesity / surgery
  • Quality of Life