The influenza universe in an mRNA vaccine

Science. 2022 Nov 25;378(6622):827-828. doi: 10.1126/science.adf0900. Epub 2022 Nov 24.

Authors

Alyson A Kelvin^{1

2}, Darryl Falzarano^{1

3}

Affiliations

¹ Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
² Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
³ Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

PMID: 36423290
DOI: 10.1126/science.adf0900

Abstract

An mRNA-lipid nanoparticle vaccine protects animals from 20 influenza lineages.

Publication types

Comment

MeSH terms

Alphainfluenzavirus* / immunology
Animals
Ferrets
Influenza B virus* / immunology
Influenza Vaccines* / genetics
Influenza Vaccines* / immunology
Influenza, Human* / prevention & control
Mice
Vaccines, Synthetic* / genetics
Vaccines, Synthetic* / immunology
mRNA Vaccines* / genetics
mRNA Vaccines* / immunology

Substances

Influenza Vaccines
Lipid Nanoparticles
mRNA Vaccines
Vaccines, Synthetic