Metallic Structures Based on Zinc Oxide Film for Enzyme Biorecognition

Micromachines (Basel). 2022 Nov 17;13(11):1997. doi: 10.3390/mi13111997.

Abstract

Two structures (Ag/ZnO/ITI/glass: #1 sample and Ag/ZnO/SiO2/Si: #2 sample) are investigated, on the one hand, from the point of view of the formation of evanescent waves in the gratings of metal strips on the structures when the incident TEz wave in the radio frequency range is used. The simulation of the formation of evanescent waves at the edge of the Ag strips, with thicknesses in the range of micrometers, was carried out before the test in the subwavelength regime, with the help of a new improved transducer with metamaterial (MM) lenses. By simulation, a field snapshot was obtained in each sequence of geometry. The evanescent waves are emphasized in the plane XY, due to the scattering of the field on the edge of the strips. On the other hand, ZnO nanoparticles are investigated as a convenient high-efficiency biodetection material, where these structures were used as a biosensitive element to various enzymes (glucose, cholesterol, uric acid, and ascorbic acid). The obtained results demonstrate that the investigated structures based on ZnO nanostructures deposited on different supports are fast and sensitive for enzyme detection and can be successfully incorporated into a device as a biosensing element.

Keywords: biomaterials; enzymes biorecognition; gratings mesostructures; multifunctional nanosystem; zinc oxide nanoparticles.

Grants and funding

This research received no external funding.