Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report

Children (Basel). 2022 Nov 17;9(11):1767. doi: 10.3390/children9111767.

Abstract

Background: We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation.

Methods: A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in an experimental way, evaluating the efficacy described in the literature (selective bibliographic search in PubMed) of the use of blood products for non-transfusion purposes.

Results: A partial but satisfactory regeneration of the patient's nasal septum was observed. Using the free NIH Image J online software, we were able to calculate the regenerated surface (about 83% of the destroyed cartilage).

Conclusions: The use of platelet gel has been a promising alternative to surgical treatment in patients with severe damage to the nasal septum.

Keywords: nasal septum; non-invasive ventilation; platelet gel; prematurity; septal tissue.

Publication types

  • Case Reports

Grants and funding

This research received no external funding.