Urinary arsenic and health risk of the residents association in contaminated-groundwater area of the urbanized coastal aquifer, Thailand

Chemosphere. 2023 Feb:313:137313. doi: 10.1016/j.chemosphere.2022.137313. Epub 2022 Nov 19.

Abstract

Determining of arsenic (As) exposure was conducted in 110 residents which divided into two groups using the WHO guidelines for As in drinking water of 10 μg/L. Moreover, questionnaires with face-to-face interviews were used to make a health risk assessment and to determine the associated factors. The median of As in urine was 61.33 μg/L (5.38-600.86 μg/L), accounting for 68.18% of participants who exposed to the contaminated groundwater had obviously high urinary As levels, exceeded the normal value of 50 μg/L of As, as set by the National Health and Nutrition Examination Survey (NHANES). The major factor affecting As in urine was the As contaminated groundwater. Pearson's chi-squared test showed that the urinary As level was influenced on the different groups of As level in groundwater (p-value <0.001). Multiple linear regression confirmed that the actual risk factors of As in urine were the As level in groundwater and the oral exposure route but not the dermal contact. Meanwhile binary logistic regression revealed that all socio-demographic factors were not influenced. Approximately 45.45% of the area had the HI above the risk level of 1, mostly via groundwater drinking pathway. The estimated total cancer risk values, 5.11 × 10-6 to 2.08 × 10-3, were higher than the safe level of 10-6. For long-term exposure, the As concentration and exposure duration were the most variables influencing health risk level. This finding suggests that chronic As exposure should be monitored and also the groundwater should be improved to provide the safe drinking water for the residents.

Keywords: Arsenic; Coastal aquifer; Groundwater drinking; Health risk assessment; Thailand; Urine sample.

MeSH terms

  • Arsenic* / analysis
  • Drinking Water* / analysis
  • Environmental Monitoring
  • Groundwater*
  • Humans
  • Nutrition Surveys
  • Risk Assessment
  • Thailand
  • Water Pollutants, Chemical* / analysis

Substances

  • Arsenic
  • Drinking Water
  • Water Pollutants, Chemical