Consensus guidelines on management of oral potentially malignant disorders

Indian J Cancer. 2022 Jul-Sep;59(3):442-453. doi: 10.4103/ijc.IJC_128_21.

Abstract

Oral cancer is usually preceded by oral potentially malignant disorders (OPMDs) and early detection can downstage the disease. The majority of OPMDs are asymptomatic in early stages and can be detected on routine oral examination. Though only a proportion of OPMDs may transform to oral squamous cell carcinoma (OSCC), they may serve as a surrogate clinical lesion to identify individuals at risk of developing OSCC. Currently, there is a scarcity of scientific evidence on specific interventions and management of OPMDs and there is no consensus regarding their management. A consensus meeting with a panel of experts was convened to frame guidelines for clinical practices and recommendations for management strategies for OPMDs. A review of literature from medical databases was conducted to provide the best possible evidence and provide recommendations in management of OPMDs.

Keywords: Consensus; management; oral leukoplakia; oral lichen planus; oral potentially malignant disorders; oral submucous fibrosis.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell* / diagnosis
  • Carcinoma, Squamous Cell* / pathology
  • Carcinoma, Squamous Cell* / therapy
  • Head and Neck Neoplasms*
  • Humans
  • Mouth Diseases* / pathology
  • Mouth Neoplasms* / diagnosis
  • Mouth Neoplasms* / pathology
  • Mouth Neoplasms* / therapy
  • Precancerous Conditions* / diagnosis
  • Precancerous Conditions* / therapy
  • Squamous Cell Carcinoma of Head and Neck