Status Asthmaticus Gravidus: Emergency and Critical Care Management of Acute Severe Asthma During Pregnancy

Charles B Cairns; Monica Kraft

doi:10.1016/j.iac.2022.07.010

Status Asthmaticus Gravidus: Emergency and Critical Care Management of Acute Severe Asthma During Pregnancy

Immunol Allergy Clin North Am. 2023 Feb;43(1):87-102. doi: 10.1016/j.iac.2022.07.010. Epub 2022 Oct 28.

Authors

Charles B Cairns¹, Monica Kraft²

Affiliations

¹ College of Medicine, Medical Affairs, Drexel University, 245 N. 15th Street, 19th Floor, Philadelphia, PA 19102, USA. Electronic address: cbc77@drexel.edu.
² Samuel Bronfman Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount. One Gustav Levy Place, PO Box 1118, Annenberg 5-02, New York, NY 10029, USA.

PMID: 36411010
DOI: 10.1016/j.iac.2022.07.010

Abstract

One-third of women with asthma have deterioration of their asthma during pregnancy, and one-fourth of pregnant women with asthma will experience severe exacerbations necessitating emergency department (ED) visits or hospitalizations. Early recognition of acute severe asthma, including life-threatening status asthmaticus, and aggressive medical interventions with β2-agonists, anticholinergic agents, and systemic corticosteroids are necessary to treat maternal airway bronchoconstriction, support maternal and fetal oxygenation, and avoid adverse fetal outcomes. This review describes management of acute severe asthma in pregnancy, including status asthmaticus, in the ED and intensive care unit.

Keywords: Acute asthma; Critical asthma syndrome; Critical care; ED; Emergency department; ICU; Pregnancy; Treatment.

Publication types

Review

MeSH terms

Asthma* / diagnosis
Asthma* / therapy
Critical Care
Family
Female
Hospitalization
Humans
Pregnancy
Status Asthmaticus* / diagnosis
Status Asthmaticus* / therapy