5-(4-Fluoro-phen-yl)-1-[4-(4-methyl-phen-yl)thia-zol-2-yl]-3-[4-(prop-2-yn-yloxy)phen-yl]-4,5-di-hydro-1 H-pyrazole

Sreeramapura D Archana; Holalagudu A Nagma Banu; Balakrishna Kalluraya; Hemmige S Yathirajan; Rishik Balerao; Ray J Butcher

doi:10.1107/S2414314622010033

5-(4-Fluoro-phen-yl)-1-[4-(4-methyl-phen-yl)thia-zol-2-yl]-3-[4-(prop-2-yn-yloxy)phen-yl]-4,5-di-hydro-1 H-pyrazole

IUCrdata. 2022 Oct 25;7(Pt 10):x221003. doi: 10.1107/S2414314622010033. eCollection 2022 Oct.

Authors

Sreeramapura D Archana¹, Holalagudu A Nagma Banu², Balakrishna Kalluraya², Hemmige S Yathirajan¹, Rishik Balerao³, Ray J Butcher⁴

Affiliations

¹ Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore 570 006, India.
² Department of Studies in Chemistry, Mangalore University, Mangalagangotri, Mangalore 574 199, India.
³ Thomas Jefferson High School for Science and Technology, 6560 Braddock Rd, Alexandria, VA 22312, USA.
⁴ Department of Chemistry, Howard University, 525 College Street NW, Washington, DC 20059, USA.

Abstract

In the title compound, C₂₈H₂₂FN₃OS, four rings are almost coplanar, with the fluorophenyl ring substantially twisted. In the extended structure, aromatic π-π stacking inter-actions between the pyrazole ring and the tolyl ring link the mol-ecules into centrosymmetric dimers.

Keywords: 4-(prop-2-ynyloxy)phenyl; crystal structure; fluorophenyl; pyrazole; thiazole.