Research Progress of Robot Technology in In situ 3D Bioprinting

Xie Neng; Shi Guohong; Shen Yuling; Xu Yuanjing; Wang Hao; Feng Haiyang; Dai Kerong; Wang Jinwu; Cao Qixin

doi:10.18063/ijb.v8i4.614

Research Progress of Robot Technology in In situ 3D Bioprinting

Int J Bioprint. 2022 Sep 13;8(4):614. doi: 10.18063/ijb.v8i4.614. eCollection 2022.

Authors

Xie Neng^{1

2}, Shi Guohong³, Shen Yuling^{3

4}, Xu Yuanjing³, Wang Hao⁵, Feng Haiyang⁶, Dai Kerong^{3

4}, Wang Jinwu^{3

4}, Cao Qixin¹

Affiliations

¹ Department of Biomedical Manufacturing and Engineering, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
² Center for Medical Devices and Cosmetics Evaluation and Inspection, Shanghai, China.
³ Department of Biomedical Instrument, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
⁴ Department of Orthopaedic Surgery, School of Medicine, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University, Shanghai, China.
⁵ Department of Mechanical Engineering, School of Mechanical and Electrical Engineering, Henan University of Technology, Zhengzhou, China.
⁶ Department of Rehabilitation Medicine and Physical Therapy, School of Rehabilitation Medicine, Weifang Medical University, Weifang, China.

Abstract

Three-dimensional (3D) bioprinting is an emerging research direction in bio-manufacturing, a landmark in the shift from traditional manufacturing to high-end manufacturing. It integrates manufacturing science, biomedicine, information technology, and material science. In situ bioprinting is a type of 3D bioprinting which aims to print tissues or organs directly on defective sites in the human body. Printed materials can grow and proliferate in the human body; therefore, the graft is similar to the target tissues or organs and could accurately match the defective site. This article mainly summarizes the current status of robotic applications in the medical field and reviews its research progress in in situ 3D bioprinting.

Keywords: In situ 3D bioprinting; Robotic bioprinting platform; Tissue engineering.

Publication types

Review