[Application of temporalis muscle flap in repair and reconstruction after the resection of tumor or necrotic foci following radiotherapy of nasopharyngeal carcinoma]

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Nov 7;57(11):1288-1293. doi: 10.3760/cma.j.cn115330-20211206-00774.
[Article in Chinese]

Abstract

Objective: To summarize and popularize the application of temporalis muscle flap in repair and reconstruction after the resection of tumor or necrotic foci following radiotherapy of nasopharyngeal carcinoma (NPC). Methods: A retrospective analysis was made on the patients treated in the Department of Otorhinolaryngology Head and Neck Surgery of Xiangya Hospital between January 2019 and March 2021 who underwent surgical resection of tumor or necrosis of NPC after radiotherapy and temporalis muscle flap repair. The effect of the repair and the patients' postoperative conditions were analyzed. Results: A total 29 patients, 19 males and 10 females, aged from 33 to 65 years old, were included in the study, and were followed up for 6-35 months. Except for 2 patients who were not followed due to bleeding or special bacterial infection, the others' temporalis muscle flap healed well and no cerebrospinal fluid rhinorrhea or massive hemorrhage occurred. After the operation, all patients had no nasopharyngeal reflux or new open rhinolalia, and in some patients, the open rhinolalia even got relieved. Except for one case of depressed temporal fossa caused by infection and followed debridement and another one case of shallowed forehead wrinkles, the appearances of the other patients were basically symmetrical. Some patients had temporary mouth opening limitation after operation, and all of them recovered after rehabilitation exercises. Conclusions: The temporalis muscle flap can protect the skull base and internal carotid artery, and improve the quality of life of patients after the resection of NPC or necrotic foci. It is a reliable pedicled flap for repairing skull base defect with simple operation procedures and relatively few complications.

目的: 总结推广颞肌瓣在鼻咽癌(nasopharyngeal carcinoma,NPC)放疗后肿瘤或坏死灶切除术后修复重建中的应用。 方法: 回顾性分析中南大学湘雅医院耳鼻咽喉头颈外科自2019年1月至2021年5月收治的接受了NPC放疗后肿瘤或坏死灶手术切除并应用颞肌瓣修复的患者资料,分析应用颞肌瓣修复的效果和患者术后的病情。 结果: 共29例患者纳入研究,其中男性19例,女性10例,年龄33~65岁,术后随访时间6~35个月。除2例因出血或特殊细菌感染未行进一步随访外,其他病例颞肌瓣均愈合良好,无脑脊液鼻漏或术腔大出血。所有患者术后均无鼻咽反流,无新发的开放性鼻音,部分患者开放性鼻音术后好转。除1例颞部感染后出现颞区凹陷外,其他患者头部外形基本对称,仅1例出现额纹减退。部分患者术后有短暂的张口受限,均经康复训练恢复。 结论: 颞肌瓣在NPC放疗后病灶切除手术中可以保护颅底和颈内动脉,改善患者生活质量。.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscles
  • Nasopharyngeal Carcinoma
  • Nasopharyngeal Neoplasms* / radiotherapy
  • Nasopharyngeal Neoplasms* / surgery
  • Necrosis
  • Plastic Surgery Procedures* / methods
  • Quality of Life
  • Retrospective Studies
  • Speech Disorders
  • Surgical Flaps / blood supply