Insights into the toxicity and biodegradation of fipronil in contaminated environment

Pankaj Bhatt; Saurabh Gangola; Sudipta Ramola; Muhammad Bilal; Kalpana Bhatt; Yaohua Huang; Zhe Zhou; Shaohua Chen

doi:10.1016/j.micres.2022.127247

Insights into the toxicity and biodegradation of fipronil in contaminated environment

Microbiol Res. 2023 Jan:266:127247. doi: 10.1016/j.micres.2022.127247. Epub 2022 Nov 1.

Authors

Pankaj Bhatt¹, Saurabh Gangola², Sudipta Ramola³, Muhammad Bilal⁴, Kalpana Bhatt⁵, Yaohua Huang⁶, Zhe Zhou⁶, Shaohua Chen⁷

Affiliations

¹ State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou 510642, China; Department of Agricultural & Biological Engineering, Purdue University, West Lafayette 47906, USA. Electronic address: pankajbhatt.bhatt472@gmail.com.
² School of Agriculture, Graphic Era Hill University, Bhimtal, 263136, Uttarakhand, India.
³ College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
⁴ Institute of Chemical Technology and Engineering, Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, PL-60695 Poznan, Poland.
⁵ Department of Food Science, Purdue University, West Lafayette 47906, USA.
⁶ State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou 510642, China; Guangdong Laboratory for Lingnan Modern Agriculture, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China.
⁷ State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou 510642, China; Guangdong Laboratory for Lingnan Modern Agriculture, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China. Electronic address: shchen@scau.edu.cn.

PMID: 36403315
DOI: 10.1016/j.micres.2022.127247

Abstract

Fipronil is a phenylpyrazole insecticide used in various agricultural, horticulture, and veterinary practices. Besides its wide range of applications, it also causes severe health hazards to the non-targeted organisms especially in developing countries. Fipronil showed hepatotoxic, nephrotoxic, neurotoxic, and altered reproductive development and endocrine system in humans and animals. Several methods have been already introduced for the removal of toxic fipronil including physicochemical and by the implementation of microorganisms. The microbial methods of fipronil degradation are the most promising and environmentally sustainable. The remediation of fipronil from the environment is an emerging task due to its enhanced residual concentration. Herein, we discuss the bioremediation potential of microbial strains in contaminated soil and water. It is shown that fipronil can be remediated from the environment using combined ecotechnologies. This review discusses the toxicity, different physico-chemical and biological methods, and sustainable developments in fipronil-contaminated agriculture and aquatic environments.

Keywords: Bioaugmentation; Bioremediation; Degradation; Fipronil; Metabolism; Toxicity.

Publication types

Review

MeSH terms

Agriculture
Animals
Biodegradation, Environmental
Humans
Insecticides* / toxicity
Pyrazoles* / toxicity

Substances

fipronil
Pyrazoles
Insecticides