Quality of Life in Sickle Cell Disease: What Matters

Marsha J Treadwell; Kofi A Anie

doi:10.1016/j.hoc.2022.06.010

Quality of Life in Sickle Cell Disease: What Matters

Hematol Oncol Clin North Am. 2022 Dec;36(6):1137-1149. doi: 10.1016/j.hoc.2022.06.010.

Authors

Marsha J Treadwell¹, Kofi A Anie²

Affiliations

¹ Department of Pediatrics, Division of Hematology, University of California San Francisco, UCSF Benioff Children's Hospital Oakland, 747 52nd Street, Oakland, CA 94609, USA. Electronic address: marsha.treadwell@ucsf.edu.
² Psychological Service Lead, Haematology and Sickle Cell Centre, London North West University Healthcare NHS Trust and Faculty of Medicine, Central Middlesex Hospital, Imperial College London, London, United Kingdom.

PMID: 36400535
DOI: 10.1016/j.hoc.2022.06.010

Abstract

Health-related quality of life (HRQoL) represents the practical effects of an illness in terms of symptoms and impacts, and of consequent treatments, as perceived by the patient. HRQoL is a complex multidimensional phenomenon in sickle cell disease (SCD) involving external stressors, thought patterns, emotional distress, physiological arousal, pain, and other complications of SCD. Social determinants of health comprise food and housing security, employment and education, and experiences of racism and discrimination; these social determinants also potentially affect health, HRQoL, and access to health care. Interventions must be implemented in partnership between individuals with SCD and their health-care providers.

Keywords: Health related quality of life; Quality of health care; Quality of life; Sickle cell disease; Social determinants of health.

Publication types

Review

MeSH terms

Anemia, Sickle Cell* / complications
Anemia, Sickle Cell* / therapy
Humans
Pain / etiology
Quality of Life* / psychology