The Prevalence of Symptomatic Congenital Cytomegalovirus Disease in Korea; A 15-Year Multicenter Study and Analysis of Big Data From National Health Insurance System

Sae Rom Choi; Kyung-Ran Kim; Sohee Son; Dong Sub Kim; Yun Sil Chang; Eun Young Cho; Mea-Young Chang; Yun-Kyung Kim; Dae Sun Jo; Jin Kyu Kim; Hye-Kyung Cho; Su Eun Park; Kyung Hee Park; Hwang Min Kim; Byung-Kook Lee; Yae-Jean Kim

doi:10.1093/jpids/piac118

The Prevalence of Symptomatic Congenital Cytomegalovirus Disease in Korea; A 15-Year Multicenter Study and Analysis of Big Data From National Health Insurance System

J Pediatric Infect Dis Soc. 2023 Feb 27;12(2):104-108. doi: 10.1093/jpids/piac118.

Authors

Sae Rom Choi¹, Kyung-Ran Kim¹, Sohee Son¹, Dong Sub Kim^{1

2}, Yun Sil Chang¹, Eun Young Cho³, Mea-Young Chang³, Yun-Kyung Kim⁴, Dae Sun Jo⁵, Jin Kyu Kim⁵, Hye-Kyung Cho⁶, Su Eun Park⁷, Kyung Hee Park⁸, Hwang Min Kim⁹, Byung-Kook Lee⁹, Yae-Jean Kim^{1

10}

Affiliations

¹ Department of Pediatrics, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.
² Department of Pediatrics, Kyungpook National University Children's Hospital, Daegu, Korea.
³ Department of Pediatrics, Chungnam National University School of Medicine, Daejeon, Korea.
⁴ Department of Pediatrics, Korea University Ansan Hospital, Ansan, Korea.
⁵ Department of Pediatrics, Jeonbuk National University Children's Hospital, Jeonju, Korea.
⁶ Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea.
⁷ Department of Pediatrics, Pusan National University Children's Hospital, Yangsan, Korea.
⁸ Department of Pediatrics, Pusan National University Hospital, Busan, Korea.
⁹ Department of Pediatrics, Yonsei University Wonju College of Medicine, Wonju, Korea.
¹⁰ Samsung Advanced Institute for Health Sciences and Technology, Seoul, Korea.

PMID: 36399091
DOI: 10.1093/jpids/piac118

Abstract

The birth prevalence of symptomatic congenital cytomegalovirus (cCMV) disease among live birth in Korea from a multicenter study was 0.06% during 2001-2015 with increasing frequency. The administrative prevalence of cCMV infection by big-data analysis from the national health insurance system was 0.01% and the average healthcare cost was US$2010 per person.

Keywords: Korea; congenital; cytomegalovirus; sensorineural hearing loss; seroprevalence.

© The Author(s) 2022. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Publication types

Multicenter Study

MeSH terms

Big Data
Cytomegalovirus
Cytomegalovirus Infections*
Hearing Loss, Sensorineural* / epidemiology
Humans
Infant
Prevalence
Republic of Korea

Abstract

Publication types

MeSH terms

Grants and funding