Autogenous particulated dentin for alveolar ridge preservation. A systematic review

Ann Anat. 2023 Feb:246:152024. doi: 10.1016/j.aanat.2022.152024. Epub 2022 Nov 14.

Abstract

Purpose: This review aimed to investigate the clinical outcomes of autogenous particulated dentin (APD) used for alveolar ridge preservation (ARP), evaluating volume gain, histologic/histomorphometric data, and associated complications.

Material and methods: The review followed PRISMA guidelines and was registered in the International Prospective Register of Systematic Reviews (PROSPERO). An automated search was made in four databases (Medline/Pubmed, Scopus, Web of Science, and Cochrane Library) supplemented by a manual search for relevant clinical articles published before March 10th, 2022. The review included human studies of at least four patients in which extraction and subsequent ARP were performed in a single surgery. Both comparative studies and studies that assessed ARP with APD exclusively were admitted. The quality of evidence was assessed with the Cochrane bias assessment tool, the Newcastle-Ottawa Quality Assessment Scale, and the Joanna Briggs Institute Critical Appraisal tool.

Results: Eleven studies fulfilled the inclusion criteria and were included for descriptive analysis, with a total of 215 patients, and 337 alveoli preserved by APD, spontaneous healing (blood clot), or other bone substitutes, obtaining comparatively less vertical and horizontal resorption when APD was used.

Conclusions: After dental extraction, autogenous dentin was effective in terms of volume maintenance, showing promising results in histologic/histomorphometric analysis, and a low complication rate. Nevertheless, few comparative studies with comparable parameters have been published and so more research providing long-term data is needed to confirm these findings.

Keywords: Alveolar process; Autografts; Dentin; Tissue graft; Tooth extraction.

Publication types

  • Systematic Review

MeSH terms

  • Alveolar Process / surgery
  • Alveolar Ridge Augmentation* / methods
  • Bone Substitutes*
  • Bone Transplantation / methods
  • Dentin
  • Humans
  • Minerals
  • Tooth Extraction
  • Tooth Socket / surgery

Substances

  • Bone Substitutes
  • Minerals