Actinomortierella wolfii: Identity and pathology

L S M Sigera; Sarah A Ahmed; Abdullah M S Al-Hatmi; P G R U M Welagedara; P I Jayasekera; Sybren de Hoog

doi:10.1016/j.mmcr.2022.10.005

Actinomortierella wolfii: Identity and pathology

Med Mycol Case Rep. 2022 Nov 4:38:48-52. doi: 10.1016/j.mmcr.2022.10.005. eCollection 2022 Dec.

Authors

L S M Sigera¹, Sarah A Ahmed², Abdullah M S Al-Hatmi^{2

3}, P G R U M Welagedara¹, P I Jayasekera¹, Sybren de Hoog²

Affiliations

¹ Department of Mycology, Medical Research Institute, Colombo, Sri Lanka.
² Center of Expertise in Mycology of Radboud University Medical Center / Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.
³ Natural and Medical Sciences Research Center, University of Nizwa, Nizwa, Oman.

Abstract

Actinomortierella wolfii (Mortierellales), formerly Mortierella wolfii, is a causative agent of bovine systemic infection and abortion. Human infections caused by this species are extremely rare. Here, we present a case of a patient with B-Cell Acute Lymphoblastic Leukemia (B-ALL) who was diagnosed with a rhinocerebral infection caused by this fungus. Amphotericin treatment of the patient proved unsuccessful. This type of disease is otherwise nearly exclusively limited to members of the order Mucorales. The taxonomy of the causative agent is discussed.

Keywords: Mortierellales; Mucormycosis; Ophthalmology; Rhinocerebral.

Publication types

Case Reports