Glomerella cingulata endophthalmitis

Nathan Gunasekaran; Kenneth R Lee; Andrew W Kam; Dominic McCall; Dale Waring; Season Yeung; Adrian T Fung

doi:10.1016/j.ajoc.2022.101744

Glomerella cingulata endophthalmitis

Am J Ophthalmol Case Rep. 2022 Nov 7:28:101744. doi: 10.1016/j.ajoc.2022.101744. eCollection 2022 Dec.

Authors

Nathan Gunasekaran¹, Kenneth R Lee¹, Andrew W Kam^{1

2

3}, Dominic McCall^{1

2}, Dale Waring⁴, Season Yeung^{1

2}, Adrian T Fung^{1

2

5

6}

Affiliations

¹ Department of Ophthalmology, Westmead Hospital, Westmead, New South Wales, Australia.
² Westmead and Central Clinical Schools, Specialty of Clinical Ophthalmology and Eye Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
³ Save Sight Institute, The University of Sydney, Sydney, New South Wales, Australia.
⁴ Department of Anatomical Pathology, Prince of Wales Hospital, Randwick, New South Wales, Australia.
⁵ The Westmead Institute for Medical Research, Westmead Hospital, Westmead, New South Wales, Australia.
⁶ Department of Ophthalmology, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia.

Abstract

Purpose: To report a case of an exogenous endophthalmitis caused by the fungal species Glomerella cingulata.

Observations: A 71-year-old male presented with an infectious keratitis that evolved into endophthalmitis. Combined cataract extraction and pars plana vitrectomy was performed and the vitreous specimen cultured Glomerella cingulata, a variant of the Colletotrichum gloeosporioides fungal species. Despite early treatment with topical, systemic and intravitreal doses of both voriconazole and amphotericin B, the patient had a poor visual and anatomical outcome.

Conclusions and importance: Glomerella cingulata may rarely cause endophthalmitis with devastating visual outcomes.

Keywords: Colletotrichum gloeosporioides; Endophthalmitis; Glomerella cingulata; Keratitis.

Publication types

Case Reports