Meta-analysis overstates benefit of antidepressant combination therapy with α2-antagonists and reuptake inhibitors in major depression

Kevin P Kennedy

doi:10.3389/fpsyt.2022.1053530

Meta-analysis overstates benefit of antidepressant combination therapy with α2-antagonists and reuptake inhibitors in major depression

Front Psychiatry. 2022 Oct 31:13:1053530. doi: 10.3389/fpsyt.2022.1053530. eCollection 2022.

Author

Kevin P Kennedy¹

Affiliation

¹ Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States.

No abstract available

Keywords: antidepressants (AD); combination (combined) therapy; major depression (MDD); meta-analysis; selective serotonergic reuptake inhibitors (SSRI); α2-antagonist.