Database for queries of melanoma cohorts with molecular and clinical data

Abstract

Large genome-scale studies are deposited in various public sequence repositories. However, their access and analysis can be non-trivial to infrequent users. Here, we present a new database connecting whole transcriptomes with clinical data for straight-forward access and analysis of patient-specific samples. Users can perform association tests of survival and gene expression across different cohorts, identify cell-type expressions, or correlate the presence of immune cells. In summary, we present a new data hub for bench scientists to perform replication and discovery studies.

Keywords: RNA-seq; data integration; immune checkpoint inhibition; immune infiltration; melanoma.