A Case of SGLT2 Inhibitor-Induced Euglycemic Diabetic Ketoacidosis

Cureus. 2022 Oct 9;14(10):e30106. doi: 10.7759/cureus.30106. eCollection 2022 Oct.

Abstract

While rare, serious adverse effects including euglycemic diabetic ketoacidosis (EDKA) have been associated with sodium-glucose cotransporter-2 inhibitor (SGLT2i) use. We present an interesting case of SGLT2i-induced EDKA occurring two years after initiation of therapy. Most patients with EDKA recover with prompt recognition and treatment. Patient education about identifying early signs remains a cornerstone of early identification and response to SGLT2i-induced EDKA.

Keywords: diabetic keto acidosis; euglycemic dka; high anion gap metabolic acidosis; sglt-2 inhibitor; sodium-glucose cotransporter-2 inhibitors.

Publication types

  • Case Reports