Pneumomediastinum and Pneumopericardium as Uncommon Complications of COVID-19 Infection: A Review Article

Cureus. 2022 Oct 13;14(10):e30244. doi: 10.7759/cureus.30244. eCollection 2022 Oct.

Abstract

There is an emerging body of literature describing an increasing incidence of pneumomediastinum and, to a lesser extent, pneumopericardium as a complication of COVID-19. However, the literature lacks information regarding patients' characteristics and a general view of this unusual condition. The purpose of this paper is to summarize the current literature on this phenomenon. In this study, we summarize the risk factors/etiology, imaging modalities, management, and prognosis of known cases in the literature. In total, 48 articles were included in the study, ranging from case reports to case series. Most patients were male (83.3%). The overall mortality rate was 27.1% and the recovery rate was 62.5%.

Keywords: air leak syndrome; barotrauma; coronavirus disease 2019; coronavirus-2; severe acute respiratory syndrome; uncommon complication.

Publication types

  • Review