Black-odorous water has become a common and widespread problem in recent decades. In this study, nine constructed wetlands (CWs) with different flow types, filters, plants, and hydraulic loadings were designed according to an orthogonal array (L9 (34), and were used for the purification of black-odorous water in summer and winter. The results showed that CWs are regarded as effective to purify black-odorous water in both seasons. Microbial degradation is the major removal pathway of pollutants in CWs during summer, while the joint effect of biodegradation and adsorption is the main treatment route during winter. Flow type and hydraulic loading appear to be the most important factors impacting the purification performance of CWs, by changing the redox condition of systems and retention time of contaminants, respectively. 'Vertical flow-zeolite filter-high loading' is proposed as the best parameter selection for CWs on the purification of black-odorous water: among them, CWs with vertical flow have better oxygen transport capacity that is conductive to aerobic processes of pollutants, zeolite substrates may adsorb more nitrogen via ion exchange, higher hydraulic loadings can extend the contact time between contaminants and filters, and regulate the water temperature for microbial activity.