Objective: To measure and compare serum levels of leptin and lipid profile parameters in primigravida women with PE and normotensive primigravida.
Study design: Analytical cross-sectional study.
Place and duration of study: Department of Physiology and Cell Biology, University of Health Sciences, Lahore, from 2018 to 2020.
Methodology: Preeclamptic (PE, group A) and normal primigravida (PG, group B) with gestational age 30-36 weeks were recruited from tertiary care hospitals. After written and informed consent, blood samples were taken. Serum was separated and stored at -80oC until processed. CBC and lipid profile of each patient was also done using automated lab machines. Serum levels of leptin were calculated by ELISA. The data was entered and analysed in SPSS version 20.
Results: The mean serum levels of leptin (ng/ml) in PE (group A) were significantly raised compared to normotensive PG (group B) at 33.44±12.91 and 4±6.20 respectively (p.