Nontunneling Full Thickness Techniques for Neoplasia

Grace E Kim; Shivangi Kothari; Uzma D Siddiqui

doi:10.1016/j.giec.2022.09.002

Nontunneling Full Thickness Techniques for Neoplasia

Gastrointest Endosc Clin N Am. 2023 Jan;33(1):155-168. doi: 10.1016/j.giec.2022.09.002.

Authors

Grace E Kim¹, Shivangi Kothari², Uzma D Siddiqui³

Affiliations

¹ Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, 15841 South Maryland Avenue MC4076, Chicago, IL 60637, USA. Electronic address: grace.kim@uchospitals.edu.
² Division of Gastroenterology/Hepatology, University of Rochester Medical Center & Strong Memorial Hospital, 2601 Elmwood Avenue, Box 646, Rochester, NY 14642, USA.
³ Section of Gastroenterology, Hepatology, and Nutrition, Center for Endoscopic Research and Therapeutics and Advanced Endoscopy Training, University of Chicago, 35700 South Maryland Avenue MC 8043, Chicago, IL 60637, USA.

PMID: 36375880
DOI: 10.1016/j.giec.2022.09.002

Abstract

Colorectal cancer is the third most common cancer worldwide and the fourth leading cause of cancer-related deaths in the world, second in the United States. Although most lesions are managed surgically especially when they have already invaded into the submucosal layer, endoscopic full-thickness resection (EFTR) has become an emerging technique that can serve as a safe and effective alternative management for locally invasive gastrointestinal cancers. This article discusses the indications and various techniques and limitations of nontunneled EFTRs of gastrointestinal cancer and reviews the current literature on the outcomes of EFTR.

Keywords: Endoscopic full-thickness resection; Full thickness resection device; Locally advanced cancer.

Publication types

Review

MeSH terms

Endoscopic Mucosal Resection* / methods
Gastrointestinal Neoplasms* / surgery
Humans
Retrospective Studies
Treatment Outcome