Structures and bioactivities of secondary metabolites from Penicillium genus since 2010

Xiaoqin Zhang; Qizhao Yin; Xuanyi Li; Xiaowan Liu; Houxing Lei; Bin Wu

doi:10.1016/j.fitote.2022.105349

Structures and bioactivities of secondary metabolites from Penicillium genus since 2010

Fitoterapia. 2022 Nov:163:105349. doi: 10.1016/j.fitote.2022.105349. Epub 2022 Nov 11.

Authors

Xiaoqin Zhang¹, Qizhao Yin², Xuanyi Li², Xiaowan Liu³, Houxing Lei¹, Bin Wu⁴

Affiliations

¹ Zhejiang Provincial Key Laboratory of Inheritance and Innovation of She Medicine, Lishui Hospital of Traditional Chinese Medicine, Lishui 323000, China.
² Ocean College, Zhejiang University, Zhoushan 321000, China.
³ The State Key Laboratory of Marine Pollution and Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR 999077, China.
⁴ Ocean College, Zhejiang University, Zhoushan 321000, China. Electronic address: wubin@zju.edu.cn.

PMID: 36375688
DOI: 10.1016/j.fitote.2022.105349

Abstract

Penicillium genus was a fungal endophyte first reported by Alexander Fleming in 1928 and attracted more attention in recent decades due to its multitudinous metabolites which possess novel skeletons, abundant bioactivities and potential in medicine. Up to now, >300 Penicillium species were found all around the world. The review summarized secondary metabolites derived from the Penicillium genus since 2010, including their chemical structures and biological activities.

Keywords: Bioactivities; Penicillium; Secondary metabolites; Structures.

Publication types

Review

MeSH terms

Molecular Structure
Penicillium* / chemistry
Secondary Metabolism