What does MYC, BCL2, and BCL6 genes 'rearranged' mean in large cell/diffuse B-cell lymphomas?

Pathol Res Pract. 2022 Dec:240:154199. doi: 10.1016/j.prp.2022.154199. Epub 2022 Nov 2.

¹ Laboratory of Oncology, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.
² Pathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
³ Laboratory of translational genomics, IRCCS Policlinico San Martino, 16132 Genova, Italy.
⁴ Pathology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.
⁵ Pathology Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy; DISC (Dipartimento di Scienze Chirurgiche e Morfologie Integrate) Università degli Studi di Genova, 16132 Genova, Italy.
⁶ Pathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100 Terni, Italy.
⁷ Pathology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy. Electronic address: paolaparente77@gmail.com.

No abstract available

Keywords: BCL2; BCL6; Diffuse B-cell Lymphomas; Gene rearrangement; Large cell B cell Lymphoma; MYC.

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