Measuring Suite for Vascular Response Monitoring during Hyperbaric Oxygen Therapy by Means of Pulse Transit Time (PTT) Analysis

Sensors (Basel). 2022 Oct 29;22(21):8295. doi: 10.3390/s22218295.

Abstract

The efficacy of hyperbaric oxygen therapy in treating wound healing disorders is well established. The obvious explanation is the presence of elevated oxygen tissue tensions during the high-pressure oxygen exposure. This explanation omits that the effective agent, elevated oxygen tension, is only present for 6.25% of the time. To investigate possible prevailing vascular changes caused by HBOT, the presented device monitors the vascular response during therapy by Pulse-Transit-Time analysis. The device allows synchronous 1 kHz ECG and PPG measurements. The data are stored in a 1 GBit flash drive and retrieved post-therapy. Normoxic measurements on the authors with and without nicotine validate the device's functionality. Measurements during HBO therapy have been successfully performed.

Keywords: human health monitoring; pulse transit time evaluation; wearable biomedical sensing.

MeSH terms

  • Blood Gas Analysis
  • Hyperbaric Oxygenation*
  • Oxygen
  • Pulse Wave Analysis

Substances

  • Oxygen

Grants and funding

This research received no external funding.