Plasma-Initiated Grafting of Bioactive Peptide onto Nano-CuO/Tencel Membrane

Polymers (Basel). 2022 Oct 24;14(21):4497. doi: 10.3390/polym14214497.

Abstract

A bioactive peptide has been successfully grafted onto nano-CuO impregnated Tencel membranes by a simple and rapid method involving a series of textile processes, and an atmospheric argon plasma treatment that requires no additional solvent or emulsifier. Surface morphology shows an apparent change from smooth, slightly roughened, and stripped with increasing plasma treatment time. The FT-IR characteristic peaks confirm the presence of the CuO nanoparticle and peptide on the extremely hydrophilic Tencel membranes that exhibit a zero-degree contact angle. Prepared nano-CuO/Tencel membranes with 90 s plasma treatment time exhibit excellent antimicrobial activity against E. coli and S. aureus, and promote fibroblast cell viability with the assistance of a grafted bioactive peptide layer on the membrane surface.

Keywords: Tencel; antimicrobial; atmospheric pressure plasma processing; bioactive peptide; copper oxide.