Iris Racemose Hemangioma Assessment with Swept Source Optical Coherence Tomography Angiography: A Feasibility Study and Stand-Alone Comparison

Filippo Confalonieri; Huy Bao Ngo; Helga Halldorsdottir Petersen; Nils Andreas Eide; Goran Petrovski

doi:10.3390/jcm11216575

Iris Racemose Hemangioma Assessment with Swept Source Optical Coherence Tomography Angiography: A Feasibility Study and Stand-Alone Comparison

J Clin Med. 2022 Nov 6;11(21):6575. doi: 10.3390/jcm11216575.

Authors

Filippo Confalonieri^{1

2

3}, Huy Bao Ngo¹, Helga Halldorsdottir Petersen¹, Nils Andreas Eide¹, Goran Petrovski^{1

2

4}

Affiliations

¹ Department of Ophthalmology, Oslo University Hospital, Kirkeveien 166, 0450 Oslo, Norway.
² Center for Eye Research and Innovative Diagnostics, Department of Ophthalmology, Institute for Clinical Medicine, University of Oslo, Kirkeveien 166, 0450 Oslo, Norway.
³ Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090 Milan, Italy.
⁴ Department of Ophthalmology, University of Split School of Medicine and University Hospital Centre, 21000 Split, Croatia.

Abstract

Purpose: To evaluate arteriovenous malformations (AVM) with swept-source (SS) optical coherence tomography (OCT) angiography (OCTA) in iris racemose hemangioma and compare it with traditional intravenous iris fluorescein angiography (IVFA).

Methods: A cross-sectional observational clinical study was conducted on patients with iris racemose hemangioma with the ZEISS PLEX Elite 9000 SS OCT & OCTA.

Results: Three eyes of three patients were imaged. Iris racemose hemangiomas demonstrated a tortuous, well-defined, and continuous course of the AVM. The ZEISS PLEX Elite 9000 SS OCT & OCTA allowed for a detailed visualization of the ARM and was superior to IVFA in depicting small caliber, fine vessels.

Conclusions: SS-OCTA may provide a dye-free, no-injection, cost-effective method comparable to spectral domain OCTA and IVFA for diagnosing and monitoring iris racemose hemangiomas for growth and vascularity.

Keywords: OCT angiography (OCTA); Swept Source Optical Coherence Tomography (SS-OCT); iris arteriovenous aneurysm; iris arteriovenous malformation; iris racemose hemangioma.

Grants and funding

This research received no external funding.