The NLRP3-Inflammasome in Health and Disease

Int J Mol Sci. 2022 Oct 28;23(21):13103. doi: 10.3390/ijms232113103.

Abstract

The nucleotide-binding domain (NOD)-, leucine-rich repeat (LRR)-, and pyrin domain (PYD)-containing protein 3, NLRP3, is a multiprotein complex belonging to the innate immune system that can be activated by pathogens or danger-associated molecular patterns [...].

Publication types

  • Editorial

MeSH terms

  • Inflammasomes* / metabolism
  • NLR Family, Pyrin Domain-Containing 3 Protein* / metabolism
  • Pyrin Domain

Substances

  • Inflammasomes
  • NLR Family, Pyrin Domain-Containing 3 Protein