Glucomannan in Dendrobium catenatum: Bioactivities, Biosynthesis and Perspective

Genes (Basel). 2022 Oct 27;13(11):1957. doi: 10.3390/genes13111957.

Abstract

Dendrobium catenatum is a classical and precious dual-use plant for both medicine and food in China. It was first recorded in Shen Nong's Herbal Classic, and has the traditional functions of nourishing yin, antipyresis, tonifying the stomach, and promoting fluid production. The stem is its medicinal part and is rich in active polysaccharide glucomannan. As an excellent dietary fiber, glucomannan has been experimentally confirmed to be involved in anti-cancer, enhancing immunity, lowering blood sugar and blood lipids, etc. Here, the status quo of the D. catenatum industry, the structure, bioactivities, biosynthesis pathway and key genes of glucomannan are systematically described to provide a crucial foundation and theoretical basis for understanding the value of D. catenatum and the potential application of glucomannan in crop biofortification.

Keywords: Dendrobium catenatum; bioactivity; biofortification; biosynthetic pathway; dietary fiber; glucomannan; hidden hunger; structure.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosynthetic Pathways
  • Dendrobium* / genetics
  • Mannans
  • Polysaccharides

Substances

  • (1-6)-alpha-glucomannan
  • Mannans
  • Polysaccharides

Grants and funding

This work was funded by National Natural Science Foundation of China (31870310), and the Major Science and Technology Projects of Breeding New Varieties of Agriculture in Zhejiang Province (2021C02074).