Cartilage Tissue Engineering: An Introduction

Martin J Stoddart; Elena Della Bella; Angela R Armiento

doi:10.1007/978-1-0716-2839-3_1

Cartilage Tissue Engineering: An Introduction

Methods Mol Biol. 2023:2598:1-7. doi: 10.1007/978-1-0716-2839-3_1.

Authors

Martin J Stoddart¹, Elena Della Bella², Angela R Armiento^{2

3}

Affiliations

¹ AO Research Institute Davos, Davos Platz, Switzerland. martin.stoddart@aofoundation.org.
² AO Research Institute Davos, Davos Platz, Switzerland.
³ UCB Pharma, Slough, UK.

PMID: 36355280
DOI: 10.1007/978-1-0716-2839-3_1

Abstract

Once damaged, cartilage has limited healing capability. This has led to a huge body of research that aims to repair or regenerate this important tissue. Despite the progress made, significant hurdles still need to be overcome. This chapter highlights some of the progress made, while elaborating on areas that need further research. The concept of translation and the route to clinical translation must be kept in mind if some of the promising preclinical research is to make it to routine clinical application.

Keywords: Cartilage; Cell source; Chondral; Preclinical models; Regenerative medicine.

MeSH terms

Cartilage, Articular*
Regenerative Medicine
Tissue Engineering*
Tissue Scaffolds