Microsatellite markers of the major histocompatibility complex genomic region of domestic camels

Ales Knoll; Jan Wijacki; Martin Plasil; Pamela A Burger; Petr Horin

doi:10.3389/fgene.2022.1015288

Microsatellite markers of the major histocompatibility complex genomic region of domestic camels

Front Genet. 2022 Oct 24:13:1015288. doi: 10.3389/fgene.2022.1015288. eCollection 2022.

Authors

Ales Knoll¹, Jan Wijacki¹, Martin Plasil^{2

3}, Pamela A Burger⁴, Petr Horin^{2

3}

Affiliations

¹ Department of Animal Morphology, Physiology and Genetics, Faculty of Agronomy, Mendel University in Brno, Brno, Czechia.
² Department of Animal Genetics, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Brno, Czechia.
³ CEITEC-VETUNI, University of Veterinary Sciences Brno, Brno, Czechia.
⁴ Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna, Vienna, Austria.

Abstract

We identified and characterized 11 polymorphic microsatellite markers suitable for routine testing (three in the MHC class I sub-region, four in MHC class II and four in the MHC class III sub-region) of dromedaries and Bactrian camels. In total, 38 dromedaries and 33 Bactrian camels were genotyped, and interspecific differences were observed in the numbers of alleles and in allelic frequencies, as well as in the observed heterozygosity. These loci may be used as markers to study the adaptive genetic diversity of the MHC region in Old World camels.

Keywords: Camelus bactrianus; Camelus dromedarius; camels; genetic diversity; major histocompatibility complex; microsatellite markers.

Abstract

Grants and funding