Retrospective study on the impact of COVID-19 lockdown on patients with type 2 diabetes in Northern Jordan

BMJ Open. 2022 Nov 8;12(11):e065148. doi: 10.1136/bmjopen-2022-065148.

Abstract

Objective: During COVID-19 pandemic, complete lockdown of cities was one of the measures implemented by governments worldwide. Lockdown had a significant impact on people's lifestyles and access and utilisation of health services. This study aimed to assess the impact of the lockdown on glycaemic control among patients with type 2 diabetes mellitus (T2DM).

Design and setting: This was a retrospective study, electronic medical records at a leading University Hospital in Northern Jordan were used to extract study data.

Participants: All outpatients with T2DM.

Primary and secondary outcome measures: Glycated haemoglobin (HbA1c), blood glucose and lipid profile for patients with T2DM, 6 months before and 6 months after the full COVID-19 lockdown.

Results: A total of 639 patients (289 (45.2%) males and 350 (54.8%) females) were included in this study. Their age ranged from 18 to 91 years, with a mean (SD) of 59.9 (13.8) years. The overall means of HbA1c (8.41 vs 8.20, <0.001), high-density lipoprotein (1.16 vs 1.12, <0.001), low-density lipoprotein (2.81 vs 2.49, <0.001) and total cholesterol (4.45 vs 4.25, p<0.001) levels were significantly higher in the period before lockdown compared with the period after the lockdown. However, triglyceride and fasting blood glucose levels were not affected significantly after the lockdown.

Conclusions: The glycaemic control and lipid profile had significantly improved after COVID-19 pandemic lockdown. The availability of medication and medical advice delivery systems (monthly medicine deliveries) during the lockdown in Jordan might have positive impact on patients with diabetes.

Keywords: COVID-19; epidemiology; general diabetes.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Glucose
  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • Communicable Disease Control
  • Diabetes Mellitus, Type 2* / epidemiology
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Jordan / epidemiology
  • Lipids
  • Male
  • Middle Aged
  • Pandemics
  • Retrospective Studies
  • Young Adult

Substances

  • Glycated Hemoglobin A
  • Blood Glucose
  • Lipids