Multiple studies on hypertrophic scar and keloid formation have led to a plethora of therapeutic strategies in order to prevent or attenuate keloid and hypertrophic scar formation. To date, preventing pathologic scarring remains undoubtedly more effective than treating it. Next to specific surgical techniques and an appropriate general aftercare of fresh wounds, a multitude of scar gels, creams, patches, and ointments are available and are being promoted for scarless wound healing. Next to silicone-based products, onion extract or cepalin has been highlighted as one potential anti-scarring agent over recent years. Based on several studies, onion extract alone or in combination with allantoin and heparin seems to alleviate the wound-healing process and appears beneficial for preventional application in fresh scars. The study data available, however, remains overall relatively poor and clearly objective data regarding this approach is widely missing.
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