Objective:To evaluate the accuracy of preoperative computed tomographic cisternography（CTC） and magnetic resonance hydrography（MRH）in the diagnosis of cerebrospinal fluid（CSF） rhinorrhea. Methods:Retrospective analysis was made on the data of 38 patients diagnosed as cerebrospinal rhinorrhea who completed preoperative HRCT, CTC and MRH examinations in the Department of Otolaryngology Head and Neck Surgery of Tianjin Huanhu Hospital from October 2016 to January 2022. The diagnostic accuracy of preoperative imaging examinations was compared according to the leak location found during operation. Results:Among all the 38 cases with CSF rhinorrhea, the detection rates of HRCT, CTC, and cranial MRH were 31.58%, 89.47%, and 60.53%, respectively. The accuracy of CTC was significantlyhigher than that of MRH （ χ²=8.49, P=0.007）, and the accuracy of MRH was significantly higher than that of HRCT （χ²=6.41, P=0.01）. Subgroup analyses were performed according to the precise positioning of cerebrospinal fluid rhinorrhea leakage. In patients with cerebrospinal fluid rhinorrhea located in ethmoid sinus, the accuracy of CTC（80.95% vs. 14.29%，P<0.01）and MRH（52.38% vs. 14.29%，P=0.02）were significantly higher than that of HRCT, but the accuracy but the difference between CTC and MRH between CTC and MRH was not statistically significant （P=0.10）. The accuracy of CTC was significantly higher than that of MRH （100.00% vs. 61.54%, P=0.04） and HRCT （100.00% vs. 53.85%, P<0.01） in patients with CSF rhinorrhea located in sphenoid sinus. However, there was no significant difference in the accuracy between MRH and HRCT （ P=1.00）. However, There was no significant difference in the accuracy of CTC, MRH and HRCT in patients with cerebrospinal fluid rhinorrhea located in frontal sinus. The accuracy of CTC and MRH was 84.62% and 57.69% respectively in 26 patients who failed to detect a CSF rhinorrhea by HRCT, and the difference was not statistically significant（χ²=4.59, P=0.06）. Conclusion:The comprehensive application of the multiple imaging methods has important guiding significance for the accurate treatment and prognosis evaluation. CTC and MRH could improve the accuracy of the localization diagnosis of cerebrospinal fluid rhinorrhea.
目的：评估术前CT脑池造影（CTC）与头颅核磁共振水成像（MRH）对脑脊液鼻漏诊断的准确性。 方法：回顾性分析天津市环湖医院耳鼻咽喉头颈外科2016年10月—2022年1月收治的确诊为脑脊液鼻漏且同时完成术前HRCT、CTC以及MRH检查的38例患者资料，结合术中发现的漏口位置比较其与术前影像学检查结果的一致性。 结果：38例脑脊液鼻漏患者中，HRCT、CTC、头颅MRH检查发现漏口的比率分别为31.58%、89.47%和60.53%，CTC的准确率高于MRH（χ²=8.49，P=0.007），MRH的准确率高于HRCT（χ²=6.41，P=0.01）。按脑脊液鼻漏漏口的发生部位进行亚组分析，脑脊液鼻漏漏口位于筛窦者中，CTC（80.95% vs.14.29%，P<0.01）与MRH（52.38% vs.14.29%，P=0.02）对漏口定位的准确率均显著高于HRCT，然而CTC与MRH之间的定位准确率差异无统计学意义（P=0.10）；在脑脊液鼻漏漏口位于蝶窦者中，CTC对漏口定位的准确率显著高于MRH（100.00% vs.61.54%，P=0.04）与HRCT（100.00% vs.53.85%，P<0.01），然而MRH与HRCT之间的定位准确率差异无统计学意义（P=1.00）；在脑脊液鼻漏漏口位于额窦者中，CTC、MRH以及HRCT之间对漏口定位的准确率差异均无统计学意义。在HRCT未能发现脑脊液鼻漏漏口的26例患者中，CTC与MRH对漏口定位的准确率分别为84.62%和57.69%，差异无统计学意义（χ²=4.59，P=0.06）。 结论：影像学检查技术的综合运用对脑脊液鼻漏的正确治疗及预后评价有重要的指导意义。CTC与MRH可提高对脑脊液鼻漏漏口定位诊断的准确率。.
Keywords: cerebrospinal fluid rhinorrhea; computed tomographic cisternography; diagnosis; magnetic resonance hydrography.
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